Look for a spot treatment with benzoyl peroxide. This can be used in AM and PM and even over makeup. Rael pimple patches are my favorite because they offer different types of patches for different types of pimples- GENIUS! This is why they're super effective. I like to wear pimple patches overnight (apply before creams and moisturizers) and also during the day if I'm not going to be out or it's not very obvious I'm wearing one!